BDBM50639670 CHEMBL5559660

SMILES CCN1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50639670   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639670(CHEMBL5559660)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639670(CHEMBL5559660)
Affinity DataKd:  8.70nMAssay Description:Binding affinity to human PTPN2 assessed as dissociation constant measured upto 300 secs by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM50639670(CHEMBL5559660)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human PTPN2 using DiFMUP as substrate by fluorescence based phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed