BDBM50640562 CHEMBL5574006::US20250353857, Compound SH-01-18

SMILES CN(CC1CCOCC1)c1ncnc2[nH]c(-c3ccccc3)cc12

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50640562   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640562BDBM50640562(CHEMBL5574006 | US20250353857, Compound SH-01-18)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CSF1R (unknown origin) using EEEIYGEFE as substrate in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640562BDBM50640562(CHEMBL5574006 | US20250353857, Compound SH-01-18)
Affinity DataIC50: 0.600nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640562BDBM50640562(CHEMBL5574006 | US20250353857, Compound SH-01-18)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640562BDBM50640562(CHEMBL5574006 | US20250353857, Compound SH-01-18)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640562BDBM50640562(CHEMBL5574006 | US20250353857, Compound SH-01-18)
Affinity DataIC50: 6nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 mM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed