BDBM50640580 CHEMBL5569733::US20250353857, Compound TIA06-003

SMILES CN(CC1CCOCC1)c1ncnc2[nH]c(-c3ccc(C4(O)COC4)cc3)cc12

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640580   

LigandChemical structure of BindingDB Monomer ID 50640580BDBM50640580(CHEMBL5569733 | US20250353857, Compound TIA06-003)
Affinity DataIC50: 0.200nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 50640580BDBM50640580(CHEMBL5569733 | US20250353857, Compound TIA06-003)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CSF1R (unknown origin) using EEEIYGEFE as substrate in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50640580BDBM50640580(CHEMBL5569733 | US20250353857, Compound TIA06-003)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed