BDBM50640748 CHEMBL5570241

SMILES COc1ccc2c(c1)NC(=O)/C2=C1\Nc2ccccc2\C1=N/OCCCNC(=O)CCn1cc(COc2ccc(N(C(=O)CCl)C(C(=O)NCCc3ccccc3)c3cccs3)cc2Cl)nn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640748   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640748(CHEMBL5570241)
Affinity DataIC50: 68nMAssay Description:Inhibition of CDK6/CyclinD3 (unknown origin) preincubated for 15 mins followed by substrate and ATP addition incubated for 10 mins by ADP-glo lumines...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640748(CHEMBL5570241)
Affinity DataIC50: 191nMAssay Description:Inhibition of CDK4/CyclinD3 (unknown origin) preincubated for 15 mins followed by substrate and ATP addition incubated for 10 mins by ADP-glo lumines...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50640748(CHEMBL5570241)
Affinity DataIC50: 543nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hr followed by NADPH and cumene hydroperoxide additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed