BDBM50640752 CHEMBL5569832

SMILES CCS(=O)(=O)Nc1cc(-c2cc(NC)c(=O)n(C)c2)cc2c1ccn2C(C)(c1ccccn1)c1ccccn1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50640752   

LigandPNGBDBM50640752(CHEMBL5569832)
Affinity DataKd:  8.10nMAssay Description:Binding affinity to his6-tagged human BRD4 BD1 (44 to 168 residues) expressed in Escherichia coli Rossetta BL21 (DE3) cells assessed as dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50640752(CHEMBL5569832)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal his6-tagged human BRD4 BD1 (44 to 168 residues) expressed in Escherichia coli Rossetta BL21 (DE3) cells incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50640752(CHEMBL5569832)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal his6-tagged human BRD4 BD2 incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50640752(CHEMBL5569832)
Affinity DataKd:  1.03E+3nMAssay Description:Binding affinity to his-tagged human BRD4 BD2 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details