BDBM50640777 CHEMBL5556484

SMILES CCC(=O)N1CC(Oc2nn(C(C)(C)C)c3ncnc(N)c23)C1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50640777   

TargetEpidermal growth factor receptor(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640777(CHEMBL5556484)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640777(CHEMBL5556484)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640777(CHEMBL5556484)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640777(CHEMBL5556484)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BLK (unknown origin) harboring cysteine at alphaD-1 position by LanthaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640777(CHEMBL5556484)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of K-10 tracer from wild type BTK in HEK293T cells expressing NanoLuc preincubated for 3 hrs followed by tracer addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50640777(CHEMBL5556484)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of K-4 tracer from wild type BLK in HEK293T cells expressing NanoLuc preincubated for 3 hrs followed by tracer addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed