BDBM50640885 CHEMBL5571635::US12398120, Example 148

SMILES Cn1ccnc1C1(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)NC(=O)NC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50640885   

LigandPNGBDBM50640885(CHEMBL5571635 | US12398120, Example 148)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant ADAMTS7 (unknown origin) using HiLyteFluor-488 DELSSMVLELRGLRT-K(QXL520)-E-NH2 as substrate incubated for 120 mins by FRET ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50640885(CHEMBL5571635 | US12398120, Example 148)
Affinity DataIC50: 3.28nMAssay Description:Purified recombinant ADAMTS-7 (as of SEQ ID No. 01 or SEQ ID No. 02) was diluted in reaction buffer (20 mM HEPES pH 8.0, 150 mM NaCl, 5 mM CaCl2, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50640885(CHEMBL5571635 | US12398120, Example 148)
Affinity DataIC50: 1.84E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/5/2025
Entry Details
US Patent