BDBM50641007 US20250223259, Example 22

SMILES CNC(=O)C(=O)[C@H](CCC(C)(F)F)NC(=O)[C@@H]1C[C@H](C(F)(F)F)CCN1C(=O)[C@@H](NC(=O)OC)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50641007   

TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50641007(US20250223259, Example 22)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of wild type recombinant SARS-CoV-2 3CLpro (1 to 306 residues) expressed in Escherichia coli (DE3) competent cells using CP488-ESATLQSGLRK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50641007(US20250223259, Example 22)
Affinity DataIC50: 10nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent