BDBM50641919 CHEMBL5566752::US20260055113, Example 28

SMILES Cn1nc(O[C@H](c2ccccc2)C(F)F)c2cc(-c3c[nH]c(=O)[nH]c3=O)nnc21

InChI Key InChIKey=HJMWVVMHJXVIHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50641919   

Target5'-nucleotidase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50641919BDBM50641919(CHEMBL5566752 | US20260055113, Example 28)
Affinity DataIC50: 0.0800nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

Target5'-nucleotidase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50641919BDBM50641919(CHEMBL5566752 | US20260055113, Example 28)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CD73 in human MDA-MB-231 cells preincubated for 30 mins followed by AMP addition and measured after 45 mins by plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed