BDBM50642113 CHEMBL5575411

SMILES O=C1N(Cc2ccc(Cl)cc2Cl)CCN1c1cncc2ccccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50642113   

TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642113(CHEMBL5575411)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant SARS-CoV-2 MPro transfected in Escherichia coli BL21 (DE3) assessed as inhibition of MCA quenching u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642113(CHEMBL5575411)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50642113(CHEMBL5575411)
Affinity DataKd:  3.68E+5nMAssay Description:Binding affinity to N-terminal His6-tagged recombinant SARS-CoV-2 MPro C145A mutant transfected in Escherichia coli BL21 (DE3) by surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed