BDBM50642432 CHEMBL5571201

SMILES CCn1cnc2c(NCc3ccc(-c4ccoc4)nc3)nc(N3CCOC[C@H]3CCO)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642432   

TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642432(CHEMBL5571201)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642432(CHEMBL5571201)
Affinity DataIC50: 3.79E+4nMAssay Description:Inhibition of hERG by auto-patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed