BDBM50642699 CHEMBL5572339

SMILES CCc1nn(CC(=O)Nc2cccc(O)c2)c(=O)c2cc3sccc3n12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50642699   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642699(CHEMBL5572339)
Affinity DataIC50: 43nMAssay Description:Inhibition of NLRP3 in PMA-differentiated human THP-1 cells assessed as reduction in IL-1beta release preincubated with compound for 1 hrs followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed