BDBM50642849 CHEMBL5575661

SMILES COc1c[nH]c(=O)c(-c2cccc([C@]3(c4nncn4C)C[C@@H](C)C3)c2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642849   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642849(CHEMBL5575661)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) Tuner cells using a FAM-lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL(Homo sapiens)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642849(CHEMBL5575661)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of cCbl (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed