BDBM50642994 CHEMBL5570087

SMILES COC(=O)c1ccc([C@@H]2[C@@H](c3ccc(F)cc3)C(=O)N2C2CCN(C(=O)n3cncn3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50642994   

TargetMonoglyceride lipase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50642994(CHEMBL5570087)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mouse MAGL using arachidonic acid as substrate preincubated with compound for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50642994(CHEMBL5570087)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50642994(CHEMBL5570087)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant MAGL (1 to 303 residues) expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50642994(CHEMBL5570087)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50642994(CHEMBL5570087)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of rat MAGL expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with compound for 20 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed