BDBM506430 US11045457, Example 30

SMILES CN1C[C@@H](NC(=O)C(C)(C)COc2ncccc2OC(F)(F)F)[C@@H](C1)c1cnn(C)c1C

InChI Key InChIKey=UMFSMEZBNPSGCV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 506430   

TargetSomatostatin receptor type 4(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 506430BDBM506430(US11045457, Example 30)
Affinity DataIC50: 15.8nMAssay Description:This membrane-based assay measures the ability of compounds to competitively inhibit binding of I-125 labeled somatostatin to SSTR4 in membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

TargetSomatostatin receptor type 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 506430BDBM506430(US11045457, Example 30)
Affinity DataIC50: 126nMAssay Description:This membrane-based assay measures the ability of compounds to competitively inhibit binding of I-125 labeled somatostatin to SSTR1 in membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent