BDBM50643289 CHEMBL5572950

SMILES Cc1c2ccc(N(C)c3ccnc(Nc4ccc(NC(=O)CCCCCCC(=O)NO)cc4)n3)cc2nn1C

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50643289   

TargetVascular endothelial growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643289(CHEMBL5572950)
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate measured after 1 hr in presence of ATP by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643289(CHEMBL5572950)
Affinity DataIC50: 18nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643289(CHEMBL5572950)
Affinity DataIC50: 94nMAssay Description:Inhibition of HDAC6 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643289(CHEMBL5572950)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed