BDBM50643658 CHEMBL5569009

SMILES Cc1cc(C(=O)Nc2cc(NC(=O)c3cc(-n4ccnc4C)cc(C(F)(F)F)c3)ccc2C)no1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50643658   

TargetTyrosine-protein kinase Lyn(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50643658(CHEMBL5569009)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of LYN (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50643658(CHEMBL5569009)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-KIT (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50643658(CHEMBL5569009)
Affinity DataIC50: 33nMAssay Description:Inhibition of human CSF1R using pEY as substrate incubated for 40 mins in presence of [gamma33P]-ATP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed