BDBM50643674 CHEMBL5574298

SMILES Cc1cc(C(=O)Nc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2C)no1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50643674   

TargetMast/stem cell growth factor receptor Kit(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50643674(CHEMBL5574298)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of c-KIT (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50643674(CHEMBL5574298)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of LYN (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50643674(CHEMBL5574298)
Affinity DataIC50: 64nMAssay Description:Inhibition of human CSF1R using pEY as substrate incubated for 40 mins in presence of [gamma33P]-ATP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed