BDBM50644115 CHEMBL5563542::US20250236589, Compound I-3

SMILES COc1cc(SCCC(F)F)c(OC)cc1CCN

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50644115   

Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

US Patent
LigandPNGBDBM50644115(CHEMBL5563542 | US20250236589, Compound I-3)
Affinity DataKi:  0.400nMAssay Description:For all experiments, serotonin (5-HT) hydrochloride was used as a positive control, and an appropriate high affinity, cold ligand (e.g., mianserin hy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644115(CHEMBL5563542 | US20250236589, Compound I-3)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644115(CHEMBL5563542 | US20250236589, Compound I-3)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

US Patent
LigandPNGBDBM50644115(CHEMBL5563542 | US20250236589, Compound I-3)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed