BDBM50644150 CHEMBL5572991

SMILES Cc1cncc(NC(=O)C(=O)N2C[C@@H](C)CC[C@@H]2c2ccccc2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50644150   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644150(CHEMBL5572991)
Affinity DataIC50: 50nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me0 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644150(CHEMBL5572991)
Affinity DataIC50: 80nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me2 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644150(CHEMBL5572991)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PRMT5 in MTAP-null human HAP1 cells incubated for 24 hrs by SDMA in-cell western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed