BDBM50644197 CHEMBL5575075

SMILES COc1cc(OC)c(Cl)c(-c2ccc3nc(Nc4ncccc4[N+](=O)[O-])ncc3c2)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50644197   

TargetFibroblast growth factor receptor 1(Human)
Eberhard Karls University Tubingen

Curated by ChEMBL
LigandPNGBDBM50644197(CHEMBL5575075)
Affinity DataEC50:  867nMAssay Description:Inhibition of full length nanoluc-fused FGFR1 transfected in HEK293T cells assessed as target engagement incubated for 3 hrs in presence of K10 trace...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Eberhard Karls University Tubingen

Curated by ChEMBL
LigandPNGBDBM50644197(CHEMBL5575075)
Affinity DataEC50:  867nMAssay Description:Inhibition of full length nanoluc-fused FGFR2 transfected in HEK293T cells assessed as target engagement incubated for 3 hrs in presence of K10 trace...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eberhard Karls University Tubingen

Curated by ChEMBL
LigandPNGBDBM50644197(CHEMBL5575075)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of N-terminal GST tagged cytoplasmic domain human FGFR4 (460 to 802 residues) expressed in Escherichia coli BL21 (DE3) using CSox as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Eberhard Karls University Tubingen

Curated by ChEMBL
LigandPNGBDBM50644197(CHEMBL5575075)
Affinity DataEC50:  1.78E+3nMAssay Description:Inhibition of full length nanoluc-fused FGFR3 transfected in HEK293T cells assessed as target engagement incubated for 3 hrs in presence of K10 trace...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Eberhard Karls University Tubingen

Curated by ChEMBL
LigandPNGBDBM50644197(CHEMBL5575075)
Affinity DataEC50:  2.26E+3nMAssay Description:Inhibition of full length nanoluc-fused FGFR4 transfected in HEK293T cells assessed as target engagement incubated for 3 hrs in presence of K10 trace...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed