BDBM50644321 CHEMBL5591366

SMILES c1ccc(Cn2nnnc2C(c2cccnc2)N2CCNCC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50644321   

TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644321(CHEMBL5591366)
Affinity DataIC50: 716nMAssay Description:Negative allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644321(CHEMBL5591366)
Affinity DataIC50: 924nMAssay Description:Negative allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as decrease in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644321(CHEMBL5591366)
Affinity DataIC50: 1.49E+3nMAssay Description:Negative allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed