BDBM50644342 CHEMBL5565003

SMILES COc1ccc2c(c1)C=C(C(=O)N2)[C@H](c3nnnn3CCc4ccccc4)N5CCN(CC5)C6CCCCC6

InChI Key InChIKey=ZVWPOIUAPXDLMB-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50644342   

TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644342BDBM50644342(CHEMBL5565003)
Affinity DataEC50:  0.890nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)