BDBM50644343 CHEMBL5570919

SMILES CN1CCN(C(C(=O)NCc2ccccc2)c2cccnc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50644343   

TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644343(CHEMBL5570919)
Affinity DataIC50: 752nMAssay Description:Negative allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as decrease in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644343(CHEMBL5570919)
Affinity DataIC50: 1.04E+3nMAssay Description:Negative allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as decrease in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed