BDBM50644378 CHEMBL5591537

SMILES Nc1nc2c(ncn2[C@H]2C[C@@H](COCCP(=O)(O)O)N(C(=O)CCP(=O)(O)O)C2)c(=O)[nH]1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50644378   

TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644378(CHEMBL5591537)
Affinity DataKi:  9nMAssay Description:Inhibition of human HGPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644378(CHEMBL5591537)
Affinity DataKi:  60nMAssay Description:Inhibition of Plasmodium falciparum HGXPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644378(CHEMBL5591537)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis HGPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetXanthine-guanine phosphoribosyltransferase(Escherichia coli (strain K12))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644378(CHEMBL5591537)
Affinity DataKi:  9.00E+3nMAssay Description:Binding affinity to Escherichia coli XGPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed