BDBM50644590 CHEMBL5590740

SMILES C[C@@H]1CN(c2ccc3c(Nc4n[nH]c5ccc(Cc6cc(F)cc(F)c6)cc45)ncnc3c2)C[C@H](C)O1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50644590   

TargetHigh affinity nerve growth factor receptor(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50644590(CHEMBL5590740)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of wild type TRKA (unknown origin) preincubated for 30 mins followed by ATP and U Light-poly GT addition and measured after 2 hrs by multi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed