BDBM50644765 CHEMBL5570210

SMILES CC(C)c1ccc(F)c2[nH]c(C(=O)N3C[C@H]4[C@@H]([C@H]3C(=O)N[C@H](C=O)C[C@@H]3CCNC3=O)C4(C)C)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50644765   

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandPNGBDBM50644765(CHEMBL5570210)
Affinity DataIC50: 22nMAssay Description:Inhibition of C-terminal 6-his tagged SARS-CoV-2 main protease expressed in Escherichia coli BL-21-Gold(DE3) cells using DabcylKTSAVLQSGFRKM-(Edan) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandPNGBDBM50644765(CHEMBL5570210)
Affinity DataIC50: 30nMAssay Description:Inhibition of SARS-CoV-1 main protease using DabcylKTSAVLQSGFRKM-(Edan) as substrate preincubated for 30 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCathepsin B(Human)
Takeda Development Center Americas, Inc

Curated by ChEMBL
LigandPNGBDBM50644765(CHEMBL5570210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Cathepsin BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed