BDBM50644788 CHEMBL5573487

SMILES CC[C@H](CO)Nc1nc(NCc2ccc(-c3ccc(C)s3)cc2)c2ncn(C(C)C)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50644788   

TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandPNGBDBM50644788(CHEMBL5573487)
Affinity DataEC50:  15nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed