BDBM50645053 CHEMBL5575335

SMILES NC(=O)c1cccc2[nH]c(-c3ccc(NCc4ccc(C(=O)Nc5ccccc5N)cc4)cc3)nc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50645053   

TargetPoly [ADP-ribose] polymerase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50645053(CHEMBL5575335)
Affinity DataIC50: 0.0220nMAssay Description:Inhibition of PARP1 (unknown origin) using histone/NAD+ as substrates by NAD/NADH-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50645053(CHEMBL5575335)
Affinity DataIC50: 1nMAssay Description:Inhibition of PARP2 (unknown origin) using histone/NAD+ as substrates by NAD/NADH-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50645053(CHEMBL5575335)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC1 (unknown origin) using p53 residues 379 to 382 [RHKK(Ac)] as fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50645053(CHEMBL5575335)
Affinity DataIC50: 147nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50645053(CHEMBL5575335)
Affinity DataIC50: 393nMAssay Description:Inhibition of HDAC3 (unknown origin) using p53 residues 379 to 382 [RHKK(Ac)] as fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed