BDBM50645536 CHEMBL5591770

SMILES COc1cnccc1-n1cc(N(c2nc(C(N)=O)c(-c3cc(C(C)=O)c[nH]3)s2)C2CC2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50645536   

TargetActivin receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of ALK4 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ALK2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 17nMAssay Description:Inhibition of ALK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-2B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 18nMAssay Description:Inhibition of ACTR2B (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 56nMAssay Description:Inhibition of ALK3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645536(CHEMBL5591770)
Affinity DataIC50: 82nMAssay Description:Inhibition of ALK6 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed