BDBM50645537 CHEMBL5594704

SMILES CC(=O)c1c[nH]c(-c2sc(N(c3cnn(-c4ccncc4F)c3)C3CC3)nc2C(N)=O)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50645537   

TargetTGF-beta receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 74nMAssay Description:Inhibition of ALK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 183nMAssay Description:Inhibition of ALK2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of ALK4 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-2B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 6.34E+3nMAssay Description:Inhibition of ACTR2B (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Carna Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50645537(CHEMBL5594704)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK6 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed