BDBM50645849 CHEMBL5594801

SMILES Nc1ccc2ncc(CN3C(=O)c4cc(F)ccc4[C@]34CCN(Cc3ccc(F)cc3)C4=O)cc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50645849   

TargetProtein arginine N-methyltransferase 5(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50645849(CHEMBL5594801)
Affinity DataIC50: 240nMAssay Description:Inhibition of PRMT5 in human HCT-116 cells with MTAP KO assessed as decrease in SMDA level incubated for 48 hrs by immunofluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed