BDBM50645960 CHEMBL5591506

SMILES Cn1nc([C@@H]2O[C@H](CO)[C@H](O)[C@H](n3cc(-c4ccc(Br)c(F)c4F)nn3)[C@H]2O)n(-c2cc(Cl)ccc2C(F)(F)F)c1=S

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50645960   

TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50645960(CHEMBL5591506)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of his-tagged N-terminal recombinant human Gal-3 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50645960(CHEMBL5591506)
Affinity DataIC50: 40nMAssay Description:Inhibition of his-tagged N-terminal recombinant mouse Gal-3 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50645960(CHEMBL5591506)
Affinity DataIC50: 750nMAssay Description:Inhibition of his-tagged N-terminal recombinant human Gal-3 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50645960(CHEMBL5591506)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of his-tagged N-terminal human Gal-1 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50645960(CHEMBL5591506)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of his-tagged N-terminal recombinant mouse Gal-3 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-9(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50645960(CHEMBL5591506)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of his-tagged N-terminal human Gal-9 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed