BDBM50645978 CHEMBL5594532

SMILES Cc1ncc(S(=O)(=O)N2CCC(c3cn4ncnc4cc3Cl)CC2)s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50645978   

TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H] N-Methylscopolamine from human recombinant M5 receptor expressed in CHO-K1 cell membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataKi:  51nMAssay Description:Displacement of [3H] N-Methylscopolamine from human recombinant M5 receptor expressed in CHO-K1 cell membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to human M2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to human M4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed