BDBM50646101 CHEMBL5591316

SMILES C[C@H]1CCCN(C1)CC2=CN3C(=NN(C3=O)c4cccc(c4)C5(CC(C5)C)c6nncn6C)C(=C2)C(F)(F)F

InChI Key InChIKey=MIDJBXBDZRDWNR-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50646101   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646101BDBM50646101(CHEMBL5591316)
Affinity DataIC50: 11nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)