BDBM50646277 CHEMBL5592115

SMILES O=C(NO)c1ccc(CNC(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc(Cl)cc3)N2CC2CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50646277   

TargetHistone deacetylase 6(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human HDAC6 using RHKKAc as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 494nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human HDAC1 using RHKKAc as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Yangling Vocational & Technical College

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human HDAC2 using RHKKAc as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Yangling Vocational & Technical College

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human HDAC3/NCOR2 using RHKKAc as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Yangling Vocational & Technical College

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Yangling Vocational & Technical College

Curated by ChEMBL
LigandPNGBDBM50646277(CHEMBL5592115)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)-K(Ac) as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed