BDBM50647419 CHEMBL5596725

SMILES O=C(NO)c1ccc(CN2C(=O)[C@@H]3CCCN3Cc3ccccc32)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50647419   

TargetHistone deacetylase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647419(CHEMBL5596725)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human HDAC7 (518 to end residues) expressed in baculovirus expression system using Boc-Lys (Tfa)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647419(CHEMBL5596725)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human full length HDAC6 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647419(CHEMBL5596725)
Affinity DataIC50: 847nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647419(CHEMBL5596725)
Affinity DataIC50: 878nMAssay Description:Inhibition of C-terminal His6/Flag-tagged recombinant human full length HDAC1 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647419(CHEMBL5596725)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human HDAC10 (2 to 631 residues) expressed in baculovirus sf9 insect cells expression system using B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647419(CHEMBL5596725)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of recombinant human full length HDAC2 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647419(CHEMBL5596725)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC11 using Boc-Lys (Tfa)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed