BDBM50648034 CHEMBL5598317

SMILES O=C(CCCCCCn1cc(Nc2ncc(Cl)c(-c3cnc4ccccn34)n2)cn1)NO

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50648034   

TargetHistone deacetylase 3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50648034(CHEMBL5598317)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant HDAC3 using Ac-Lys-Tyr-Lys(eta-acetyl)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50648034(CHEMBL5598317)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(eta-acetyl)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate reader ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50648034(CHEMBL5598317)
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Lys-Tyr-Lys(eta-acetyl)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50648034(CHEMBL5598317)
Affinity DataIC50: 687nMAssay Description:Inhibition of CDK9 (unknown origin) using ULight 4EBP1 peptide as substrate incubated for 2 hrs in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50648034(CHEMBL5598317)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of CDK2 (unknown origin) using ULight 4EBP1 peptide as substrate incubated for 2 hrs in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50648034(CHEMBL5598317)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of CDK7 (unknown origin) using ULight 4EBP1 peptide as substrate incubated for 2 hrs in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50648034(CHEMBL5598317)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC4 using Ac-Leu-Gly-Lys(Tfa)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate reader ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed