BDBM50648995 CHEMBL5618301

SMILES CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(NCCCCCCC(=O)NO)n2)s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50648995   

TargetSerine/threonine-protein kinase B-raf(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of wild type BRAF (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 4nMAssay Description:Inhibition of wild type B-RAF (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 740nMAssay Description:Inhibition of human recombinant HDAC2 using fluorogenic HDAC substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 930nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant HDAC7 using fluorogenic HDAC substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 5.28E+4nMAssay Description:Inhibition of human recombinant HDAC5 using fluorogenic HDAC substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50648995(CHEMBL5618301)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC4 using fluorogenic HDAC substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed