BDBM50649041 CHEMBL5618160

SMILES CCc1nc2c([C@@H](C)Nc3ccc(Cl)nc3C(=O)O)cc(C)cc2c2nc(C)cn12

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50649041   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Ural Federal University

Curated by ChEMBL

LigandBDBM50649041(CHEMBL5618160)Copy SMILES

Affinity DataIC50: 84nMAssay Description:Inhibition of PI3Kalpha H1047R mutant in human MDA-MB-453 cells using PIP2 as substrate pre-incubated for 15 mins followed by substrate addition and ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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