BDBM50649147 CHEMBL5620212

SMILES N#C[C@@]1(c2ccc3c(NC(=O)c4ccc(NC(=N)N)cc4)ncnn23)O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649147   

TargetTransmembrane protease serine 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50649147(CHEMBL5620212)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human TMPRSS2 using fluorogenic substrate preincubated with enzyme in dark for 45 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50649147(CHEMBL5620212)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of SARS-CoV-2 recombinant RdRp preincubated with enzyme for 15 mins followed by single stranded polyribonucleotide template and NTPs addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed