BDBM50649576 CHEMBL5618117

SMILES CO[C@@H]1CCN(c2cc(-n3ncc4ccc([C@]5(C)CC56CC6)cc43)ncn2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649576   

LigandPNGBDBM50649576(CHEMBL5618117)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LRRK2 G2019S mutant in human SH-SY5Y cells assessed as LRRK2 pSer935 phosphorylation incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50649576(CHEMBL5618117)
Affinity DataIC50: 300nMAssay Description:Inhibition of human BCRP extracted from HEK293 cells membrane assessed as reduction in [3H]-rosuvastatin uptake preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed