BDBM50650320 CHEMBL5629856

SMILES COc1ccc2nc(NC(=O)Nc3ccc(O)c(C(F)(F)F)c3)sc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50650320   

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50650320(CHEMBL5629856)
Affinity DataKi:  440nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50650320(CHEMBL5629856)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Sus scrofa)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50650320(CHEMBL5629856)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of pig brain mitochondrial MAO-A using [3H]5-HT as substrate incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed