BDBM50650898 CHEMBL5632713

SMILES COc1cc2cc(C(=O)Oc3ccc4cc(C(=N)N)ccc4c3)c(=O)oc2cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50650898   

TargetCoagulation factor XII(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  62nMAssay Description:Inhibition of beta-FXIIa in human plasma using S-2302 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProthrombin(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  100nMAssay Description:Inhibition of human thrombin incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlasminogen(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  106nMAssay Description:Inhibition of human plasmin using S-2366 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor XI(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  8.64E+3nMAssay Description:Inhibition of human FXIa using S-2366 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi:  1.32E+4nMAssay Description:Inhibition of human Fxa using pNAPEP-8503 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetChymotrypsinogen A(Bovine)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of bovine alpha-chymotrypsin using N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTissue-type plasminogen activator(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50650898(CHEMBL5632713)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human tissue plasminogen activator using ppNAPEP-9101 as substrate incubated for 10 mins by chromogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed