BDBM50650929 CHEMBL5634034

SMILES NC(=O)c1cccc2[nH]c(NC(=O)c3cccc(C(=O)N4CCC(Nc5ncc(Br)cn5)CC4)c3)nc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50650929   

TargetPoly [ADP-ribose] polymerase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50650929(CHEMBL5634034)
Affinity DataIC50: 32nMAssay Description:Inhibition of PARP2 (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50650929(CHEMBL5634034)
Affinity DataIC50: 37nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50650929(CHEMBL5634034)
Affinity DataIC50: 344nMAssay Description:Inhibition of CDK12 (unknown origin) in presence of ATP by kinase-glo plus luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed