BDBM50651068 CHEMBL5631610

SMILES N#Cc1c(-c2ccc(Cl)cc2Cl)cc(-c2c[nH]c3ccccc23)[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50651068   

TargetEpidermal growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50651068(CHEMBL5631610)
Affinity DataIC50: 69nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50651068(CHEMBL5631610)
Affinity DataIC50: 83nMAssay Description:Inhibition of B-RAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50651068(CHEMBL5631610)
Affinity DataIC50: 95nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50651068(CHEMBL5631610)
Affinity DataIC50: 112nMAssay Description:Inhibition of wild type B-RAF (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50651068(CHEMBL5631610)
Affinity DataIC50: 184nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50651068(CHEMBL5631610)
Affinity DataIC50: 205nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50651068(CHEMBL5631610)
Affinity DataIC50: 281nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed