BDBM50651608 CHEMBL5633446

SMILES Cc1ccc(NC2(C#N)CCN(CCc3ccc(S(N)(=O)=O)cc3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50651608   

TargetCarbonic anhydrase 2(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  8.5nMAssay Description:Inhibition of recombinant human CA-II incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCarbonic anhydrase 7(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  9.40nMAssay Description:Inhibition of recombinant human CA-VII incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  36nMAssay Description:Inhibition of recombinant human CA-IX incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  49nMAssay Description:Inhibition of recombinant human CA-XII incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  60nMAssay Description:Inhibition of recombinant human CA-I incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCarbonic anhydrase 14(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  60nMAssay Description:Inhibition of recombinant human CA-XIV incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  261nMAssay Description:Inhibition of recombinant human CA-VA incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membrane by liquid scintillation counter analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCarbonic anhydrase 13(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  3.37E+3nMAssay Description:Inhibition of recombinant human CA-XIII incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)TBA
LigandPNGBDBM50651608(CHEMBL5633446)
Affinity DataKi:  9.17E+3nMAssay Description:Inhibition of recombinant human CA-IV incubated for 15 mins by stop-flow methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed