BDBM50652484 CHEMBL5641843

SMILES Cc1nn2c(-c3ccc(Br)cc3)ccnc2c1/C(N)=N/O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50652484   

TargetSerine/threonine-protein kinase Chk1(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652484(CHEMBL5641843)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase II subunit alpha(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652484(CHEMBL5641843)
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652484(CHEMBL5641843)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652484(CHEMBL5641843)
Affinity DataIC50: 442nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652484(CHEMBL5641843)
Affinity DataIC50: 590nMAssay Description:Inhibition of human CDK2 by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed