BDBM50652781 CHEMBL5649160

SMILES C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(-c5nc(CC(C)C)c(=O)[nH]c5-c5ccccc5)cc4)CC3)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50652781   

TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652781(CHEMBL5649160)
Affinity DataIC50: 490nMAssay Description:Inhibition of N-terminal His6-tagged TEV protease fused wild-type AKT1 (2 to 446 residues) (unknown origin) expressed in Sf9 cells by HTRF KinEASE as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652781(CHEMBL5649160)
Affinity DataKi:  1.24E+3nMAssay Description:Binding affinity to N-terminal His6-tagged TEV protease fused wild-type AKT1 (2 to 446 residues) (unknown origin) expressed in Sf9 cells assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652781(CHEMBL5649160)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged TEV protease fused wild-type AKT2 (2 to 447 residues) (unknown origin) expressed in Sf9 cells by HTRF KinEASE as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652781(CHEMBL5649160)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of wild-type AKT3 (unknown origin) by HTRF KinEASE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed