BDBM50652787 CHEMBL5649156

SMILES C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(-c5[nH]c(=O)c(Cc6ccc(O)cc6)nc5-c5ccccc5)cc4)CC3)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50652787   

TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652787(CHEMBL5649156)
Affinity DataKi:  755nMAssay Description:Binding affinity to N-terminal His6-tagged TEV protease fused wild-type AKT1 (2 to 446 residues) (unknown origin) expressed in Sf9 cells assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652787(CHEMBL5649156)
Affinity DataIC50: 813nMAssay Description:Inhibition of N-terminal His6-tagged TEV protease fused wild-type AKT1 (2 to 446 residues) (unknown origin) expressed in Sf9 cells by HTRF KinEASE as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652787(CHEMBL5649156)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of wild-type AKT3 (unknown origin) by HTRF KinEASE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50652787(CHEMBL5649156)
Affinity DataIC50: 5.03E+3nMAssay Description:Inhibition of N-terminal His6-tagged TEV protease fused wild-type AKT2 (2 to 447 residues) (unknown origin) expressed in Sf9 cells by HTRF KinEASE as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed